World Number One Rory McIlroy will begin his bid to become just the third person to win back to back World Golf Championships titles when he tees it up at this week's WGC - Mexico Championship on Thursday morning.
The Northern Irishman, who won the WGC-HSBC Champions title in November when he overcame Xander Schauffele in a play-off to claim a third World Golf Championships crown, is in a star studded 72 man field gathered at Chapultepec Golf Club this week.
Englishman Fleetwood has happy memories of the 2017 edition of this event, when he finished second behind Dustin Johnson.
Fleetwood, who went on to win the Race to Dubai that year, has performed well at this tournament ever since and is delighted to be back.
He said: "Great memories. It was the start of me obviously kicking on and the second stage of my career, if you like.
"I had a very special weekend, played great and holed a monster putt on the last which at the time was the biggest cheque by a mile that I'd ever had.
"That first year was great and I've played well in the times it's been here since - obviously not had the results but I can do a lot of good things around here so hopefully we can do it again.
"It is a week we look forward to."
Last year's winner Johnson is back in Mexico this week with a view to emulating Tiger Woods' achievement of successfully defending a WGC title, and he will get his first round under way alongside European Ryder Cup star Francesco Molinari and local favourite Abraham Ancer from the tenth tee at 1139.
The American cruised to a dominant five shot victory 12 months ago, thanks to bogey free rounds of 64 and 67 on Thursday and Friday and weekend 66s.
Spaniard Jon Rahm is among the afternoon starters, teeing off in the company of Australian Adam Scott and Mexico's Carlos Ortiz at 1303, just before 2019 Open Championship winner Shane Lowry, Jordan Spieth and Sung Kang at 1315.
Lucas Herbert, who picked up his maiden European Tour title at the 2020 Omega Dubai Desert Classic last month, will make his WGC debut from the first tee at 1215.